The question "Ginger or Mary Ann?" is considered a classic pop-psychological question when given to American men of a certain age as an insight into their characters, or at least their desires as regarding certain female stereotypes. With the January 2014 death of Gilligan's Island co-star Russell Johnson, Louise and actress Dawn Wells are the only two surviving cast members of the original sitcom. Louise is quoted as saying, "The best movie you'll ever be in is your own life because that's what matters in the end."
Louise declined to participate in any of three reunion television films for Gilligan's Island. Despite maintaining an adequate career after the show's run, she kept claiming that the show actually ruined her career. The role of Ginger was recast with Judith Baldwin and Constance Forslund. Although she did not appear in these television movies, she made brief walk-on appearances on a few talk shows and specials for Gilligan's Island reunions, including Good Morning America (1982), The Late Show (1988) and the 2004 TV Land award show with the other surviving cast members. In the 1990s, she was reunited with costars Bob Denver, Dawn Wells, and Russell Johnson in an episode of Roseanne. She did not reunite with them for the television film Surviving Gilligan's Island (2001), co-produced by Wells. She was portrayed by Kristen Dalton in the television film. Her relations with series star Denver were rumored to be strained, but in 2005, she wrote a brief, affectionate memorial to him in the year-end "farewell" issue of Entertainment Weekly.