Rule Sets

Been thinking of the future campaign. Need to decide something important. The rules. My go to is RC. (Thats Dungeons & Dragons Rules Cyclopedia for those of you not in the know) But then I think maybe should use S&W, or Microlite 20. I find both of those super easy to hack, spindle, fold, and mutilate into any shape I like. Then I think, well get away from the D&D/OSR sets and go different. Like open D6 or Uni-system. Then finally I think well why not use one of the couple different rules sets that I've written or pondered for myself. So many choices need to decide....... Tough choice.